Real-time Polymerase Chain Reaction:Article Title: Therapeutic potential of allosteric HECT E3 ligase inhibition.
Article Snippet: .. PDB: SMURF2 - compound 8 complex: 9FSH Experimental models: Cell lines Mammalian HEK293 cells ATCC CatCRL-1573 primary human pulmonary arterial smooth muscle cells Royal Papworth Hospital Research Tissue Bank research ethics: 08/H0304/56+5 primary human pulmonary arterial endothelial cells Lonza Cat#CC-2530 Experimental models: Organisms/strains Wistar Kyoto rats (WKY/NHsd) Harlan (now Inotiv) Cat#023 SU5416 Sigma Cat#S8442 Crotaline Sigma Cat#C2401 Oligonucleotides ACVRL1 (siRNA) Thermo Fisher Scientific Assay ID: VHS41062, Cat#1299001 BMPR2 (siRNA) Thermo Fisher Scientific Assay ID: S2044, Cat#4390824 ENG (siRNA) Thermo Fisher Scientific Assay ID: S4677, Cat#4392420 SMAD9 (siRNA) Thermo Fisher Scientific Assay ID: S8415, Cat#4392420 SMURF1 (siRNA) Thermo Fisher Scientific Assay ID: S32798, Cat#4390824 SMURF1 qPCR probe Thermo Fisher Scientific Hs00410929_m1 Software and algorithms DiscoverX PathHunter Eurofins N/A COOT Global Phasing Ltd. N/A BUSTER Global Phasing Ltd. N/A PyMOL DeLano Scientific LLC N/A Incucyte S4 live cell imager Sartorius N/A ProteomeDiscoverer (PD) ver. .. 2.4 Thermo Fisher Scientific N/A clusterProfiler Mund et al.90 N/A MetabaseMap GeneGO, Clarivate N/A MSigDB Broad Institute, Cambridge N/A ImagePro Media Cybernetics N/A HHblits Max Planck Institute N/A ll Please cite this article in press as: Rothman et al., Therapeutic potential of allosteric HECT E3 ligase inhibition, Cell (2025), https://doi.org/ 10.1016/j.cell.2025.03.001
Software:Article Title: Therapeutic potential of allosteric HECT E3 ligase inhibition.
Article Snippet: .. PDB: SMURF2 - compound 8 complex: 9FSH Experimental models: Cell lines Mammalian HEK293 cells ATCC CatCRL-1573 primary human pulmonary arterial smooth muscle cells Royal Papworth Hospital Research Tissue Bank research ethics: 08/H0304/56+5 primary human pulmonary arterial endothelial cells Lonza Cat#CC-2530 Experimental models: Organisms/strains Wistar Kyoto rats (WKY/NHsd) Harlan (now Inotiv) Cat#023 SU5416 Sigma Cat#S8442 Crotaline Sigma Cat#C2401 Oligonucleotides ACVRL1 (siRNA) Thermo Fisher Scientific Assay ID: VHS41062, Cat#1299001 BMPR2 (siRNA) Thermo Fisher Scientific Assay ID: S2044, Cat#4390824 ENG (siRNA) Thermo Fisher Scientific Assay ID: S4677, Cat#4392420 SMAD9 (siRNA) Thermo Fisher Scientific Assay ID: S8415, Cat#4392420 SMURF1 (siRNA) Thermo Fisher Scientific Assay ID: S32798, Cat#4390824 SMURF1 qPCR probe Thermo Fisher Scientific Hs00410929_m1 Software and algorithms DiscoverX PathHunter Eurofins N/A COOT Global Phasing Ltd. N/A BUSTER Global Phasing Ltd. N/A PyMOL DeLano Scientific LLC N/A Incucyte S4 live cell imager Sartorius N/A ProteomeDiscoverer (PD) ver. .. 2.4 Thermo Fisher Scientific N/A clusterProfiler Mund et al.90 N/A MetabaseMap GeneGO, Clarivate N/A MSigDB Broad Institute, Cambridge N/A ImagePro Media Cybernetics N/A HHblits Max Planck Institute N/A ll Please cite this article in press as: Rothman et al., Therapeutic potential of allosteric HECT E3 ligase inhibition, Cell (2025), https://doi.org/ 10.1016/j.cell.2025.03.001
|
ATCC is a verified supplier 
ATCC manufactures this product 